In striving for a better world by 2030, all the Sustainable Development Goals (SDGs) should be met, not just one. However, the need to identify and pursue the SDGs in line with the developmental needs of developing economies has arisen as a result of the significant interactions (the synergies and trade-offs) between the SDGs. This study's overarching goal is to objectively explore the connection between a subset of the UN SDGs and national wealth as a surrogate for economic well-being among ASEAN member states. The primary objective of this research is to identify the elements that either amplify or dampen the link between a country's level of economic prosperity and its level of scientific achievement. We employ multiple regression analysis to examine the link between the SDGs and national income. While the correlation between GDP and HDI and the SDGs is weak, the correlation between Total Country Wealth and the SDGs is strong. Based on the findings, ASEAN nations should prioritize sustainability and provide more resources to their management because of its direct effect on national wealth. As a bloc, sustainability seems to have a direct impact on ASEAN total wealth. This is significant as the stakeholders must align their policies, economic development and community integrations with a more sustainable approach for a harmonious coexistence over the medium to long term.